Chalmers holds a B.S. in Engineering from Stanford University and an M.F.A. in Painting from the Royal College of Art, London. She has exhibited her artwork around the world, including MoMA P.S.1; MassMoca; Kunsthalle Vienna; Today Art Museum, Beijing. Her work has been featured in the New York Times, Washington Post, Time Out New York, ArtNews, Artforum and on PBS, CNN, NPR, and the BBC. Two books have been published on her work: FOOD CHAIN (Aperture 2000) and AMERICAN COCKROACH (Aperture 2004). Her video Safari won Best Experimental Short at SXSW Film Festival in 2008. In 2010 Chalmers received at Guggenheim Fellowship and in 2015 she was awarded a Rauschenberg Residency. In 2018 she created a course for Stanford University, Art & Environmental Engagement, and taught it spring quarter. Her video Leafcutters won Best Environmental Short at the 2018 Natourale Film Festival, Wiesbaden, Germany. She lives in New York City.