As addiction to the opioid fentanyl surges in the U.S. causing an unprecedented number of overdoses, violence spikes in the mountains of Guerrero, Mexico. Fentanyl is cheaper and more potent, which has slashed natural opium prices, leaving the indigenous poppy farmers in Guerrero left with few options for survival. Poppy Crash chronicles the stories of three indigenous farmers who worked in the opium harvest since they were children and suddenly had their livelihood ripped out from under them. Their dependence on the international drug economy and the volatile market has left these communities with an uncertain future where increased poverty and violence is evident.